其研究成果以第一作者或通讯作者发表在 Nature Nanotechnology, Nature Communication, Cancer Research, Angew. Chem. Int. Ed, Advanced material, Advanced Science 等国际知名杂志中。申请专利5项，授权3项。主持国家自然科学面上基金2项、基金青年基金1项、上海市科委项目3项。
He has published multiple papers in high profile journals such as Nature Nanotechnology, Nature communication, Cancer research, Advanced Science, Angew. Chem. Int. Ed. et. al., applied 5 patents (authorized 3) and got grant supports from the National Natural Science Foundation of China and the Key Project of Shanghai Science and Technology Commission.
【主要承担的科研项目（项目负责人）】
1. 国家自然科学基金面上项目，活性金属硼化物治疗痛性糖尿病周围神经病变的机制研究。项目号：82372122，2024.01-2027.12，资助金额48万，主持
2. 国家自然科学基金面上项目，基于层状硼化物的糖调控系统用于糖尿病感染创面修复的研究。项目号：82172091，2022.01-2025.12，资助金额55万，主持
3. 上海市“科技创新行动计划”优秀学术带头人计划，新型硼化物动态调控离子电流用于糖尿病神经疼痛的高效治疗。项目号：23XD1422800，2023.01-2025.12，资助金额40万，主持
4. 上海市“科技创新行动计划” 生物医药支撑项目，“硼磁”糖尿病创面新型敷料研发。项目号：23S31900200，2023.01-2025.12，资助金额 25万，主持
5. 上海市基础项目子课题1项，化学动力学疗法的分子生物学功能及机制研究。项目号：19JC1412002。2019.11.01-2022.10.31，资助金额150万，主持
6. 国自然院内培育面上A类1项，糖尿病创面炎症的功能和机制研究。项目号：04.03.19.104。2020.01-2022.12，资助金额10万，主持，在研
7. 上海市基础项目子课题1项，化学动力学疗法的分子生物学功能及机制研究。项目号：19JC1412002。2019.11.01-2022.10.31，资助金额150万，主持，在研
8. 院内人才引进项目1项，资助金额30万，主持，在研
9. 国家自然科学基金青年项目1项，TLR2调节IL-33抵抗细菌感染的功能和机制研究。项目号：81202327。 2013.1-2015.12，资助金额23万，主持
【论文列表（Publication List）】
1. Yang Chen#, Chaochao Wang#, Yelin Wu#, Ya Wang, Yun Meng, Fan Wu, Huilin Zhang, Yuen Yee Cheng, Xingwu Jiang, Jieyun Shi, Huiyan Li, Peiran Zhao, Jinfeng Wu*, Bin Zheng, Dayong Jin*, Wenbo Bu*. Nutrient-Delivery and Metabolism Reactivation Therapy for Melanoma. 2024，Nature Nanotechnology. IF38.3
2. Yun Meng#, Lijie Chen #, Yang Chen#, Jieyun Shi, Zheng Zhang, Yiwen Wang, Fan Wu, Xingwu Jiang, Wei Yang, Li Zhang , Chaochao Wang, Xianfu Meng, Yelin Wu*, Wenbo Bu* Reactive Metal Boride Nanoparticles Trap Lipopolysaccharide and Peptidoglycan for Bacteria-Infected Wound Healing. Nature communications, 2022, 13(1):7353. IF 17.694
3. Yelin Wu#, Yanchun Quan#, Yuanqi Liu, Keiwei Liu, Hongquan Li, Ziwei Jiang, Tian Zhang, Hu Lei, K atherine A. Radek, Dongqing Li, Zhenhua Wang, Jilong Lu, Wang Wang, Shizhao Ji, Zhaofan Xia, Yuping Lai. Hyperglycemia inhibits REG3A expression to exacerbate TLR3-mediated skin inflammation in diabetes. Nature Communications, 2016 Nov 10; 7:13393. doi: 10.1038/ncomms13393. IF IF 17.694
4. Fan Wu, Yanli Li,Yun Meng, Xuechao Cai, Jieyun Shi,Jinjin Li, Yang Chen, Li Zhang, Xianfu Meng, Huiyan Li, Xingwu Jiang, Zhenxiao Fu, Yelin Wu,* Wenbo Bu*. An Ion-enhanced Oncolytic Virus-like nanoparticle for Tumor Immunotherapy. Angew. Chem. Int. Ed. 2022, e202210487. IF 16.823
5. Zhongmin Tang, Shiman Wu, Peiran Zhao, Han Wang, Dalong Ni, Huiyan Li,Xingwu Jiang, Yelin Wu,* Yun Meng, Zhenwei Yao,* Weibo Cai, and Wenbo Bu*.Chemical Factory-guaranteed Enhanced Chemodynamic Therapy for Orthotopic Liver Cancer. Adv. Sci. 2022, 2201232. doi.org/10.1002/advs.202201232. IF 17.521
6. Kun Wang, Jinjin Li, Yan Yi, Bin Lv, Yelin Wu*, Chaochao Wang, Huiyan Li, Yanli Li, Yang Liu,a Xuechao Cai, Xianfu Meng, Xingwu Jiang, Xiangpeng Zheng,* Zhaocai Zhou, and Wenbo Bu*. Polyamine-activated carbonyl stress strategy for oxidative damage therapy. Nano Today. 42 (2022) 101355. Doi.org/10.1016/j.nantod.2021.101355. IF 18.962
7. Hu Lei, Yue Wang, Tian Zhang, Leilei Chang, *Yelin Wu, *Yuping Lai.TLR3 activation induces S100A7 to regulate keratinocyte differentiation after skin injury. SCIENCE CHINA Life Sciences. 2017 Feb; 60(2):158-167. doi: 10.1007/s11427-016-0027-2. IF 10.372
8. Yelin Wu, Yanli Li, Guanglei Lv and Wenbo Bu. Redox dyshomeostasis strategy for tumor therapy based on nanomaterials chemistry. DOI: 10.1039/d1sc06315d. Chemical Sci. 2022 Feb 23; 13(8): 2202-2217.IF 9.969
9. Xuechao Cai#, Xiaogang Bao#, Yelin Wu.* Metal–Organic Frameworks as Intelligent Drug Nanocarriers for Cancer Therapy. Pharmaceutics 2022, 14(12), 2641; https://doi.org/10.3390/pharmaceutics14122641. IF 6.525
10. Xianfu Meng, *Yelin Wu, and *Wenbo Bu. Functional CT Contrast Nanoagents for the Tumor Microenvironment. Advanced Healthcare Materials. 2020; 2000912. IF 11.092.
11. Fan Wu, Yang Liu, Hui Cheng, Yun Meng, Jieyun Shi, Yang Chen，Yelin Wu*. Enhanced Cancer Starvation Therapy Based on Glucose Oxidase/3-Methyladenine-Loaded Dendritic Mesoporous Organosilicon Nanoparticles. Biomolecules 2021, 11,1363. IF 6.978
12. Zhenhua Wang, Xiaogang Bao, Junjie Hu, Sibo Shen, Guohua Xu, Yelin Wu*. Nicotinamide Riboside Enhances Endothelial Precursor Cell Function to Promote Refractory Wound Healing Through Mediating the Sirt1/AMPK Pathway. 2021. Front Pharmacol. 2021 May 12; 12:671563. doi: 10.3389/fphar.2021.671563. IF 6.064
13. Yanli Li, Peiran Zhao, Teng Gong*, Han Wang, Xingwu Jiang, Hui Cheng, Yanyan Liu, Yelin Wu*, Wenbo Bu* Redox Dyshomeostasis Strategy for Hypoxic Tumor Therapy Based on DNAzyme‐Loaded Electrophilic ZIFs. 2020. Angew. Chem. Int. Ed. 2020 Dec7;59(50):22537-22543, DOI: 10.1002/anie.202003653. IF 16.823
14. Weiwei Su, Han Wang, Tao Wang, Xiao Li, Zhongmin Tang, Shuai Zhao, Meng Zhang, Danni Li, Xingwu Jiang, Teng Gong, Wei Yang, Changjing Zuo,* Yelin Wu,* Wenbo Bu*. Auger Electrons Constructed Active Sites on Nanocatalysts for Catalytic Internal Radiotherapy. Advanced Science. 2020.7.1903585. IF 17.521
15. Li Qin#, Ye-lin Wu#, Michael J. Toneff, Dabing Li, Lan Liao, Xiuhua Gao, Jean C-Y. Tien, Yixiang Xu, Zhen Feng, Suoling Zhou, Yi Li, and Jianming Xu. NCOA1 directly targets M-CSF1 expression to promote breast cancer metastasis. Cancer Res. 2014 Jul 25;74(13):3477-88 (Co-first author) IF 13.312
16. Miao Xu, Huiping Lu, Young-Hee Lee, Yelin Wu, Kewei Liu, Yuling Shi, Haoran An, Jingren Zhang, Xiaohu Wang, Yeping Lai, Chen Dong. An An Interleukin-25-Mediated Autoregulatory Circuit in Keratinocytes Plays a Pivotal Role in Psoriatic Skin Inflammation. Immunity: 48(2018)1-12.
17. Lai Y‚ Li D‚ Li C‚ Muhleisen B‚ Radek KA‚ Park HJ‚ Jiang Z‚ Li Z‚ Lei H‚ Quan Y‚ Zhang T‚ Wu Y, Kotol P‚ Morizane S‚ Hata TR‚ Iwatsuki K‚ Tang C‚ Gallo RL. The antimicrobialprotein REG3A regulates keratinocyte proliferation and differentiation after skin injury. Immunity: 37(2012)74-84.
