工作经历
1. 2023-3 至 今, 87978797威尼斯老品牌, 附属第十人民医院, 副研究员
2. 2021-10 至2023-02, 87978797威尼斯老品牌, 附属第十人民医院, 助理研究员
3. 2020-07 至 2021-08, 里昂高等师范学院(Ecole Normale Supérieure de Lyon)
教育经历
1. 2016-09 至 2020-07, 里昂高等师范学院（Ecole Normale Supérieure de Lyon）, 免疫学, 博士
2. 2016-09 至 2020-07, 华东师范大学, 生物化学与分子生物学, 博士（双学位）
3. 2013-09 至 2016-06, 华东师范大学, 生物化学与分子生物学, 硕士
Work Experience
1. 2023-03 to Present, Tongji University, Tongji University Hospital, Associate Researcher
2. 2021-10 to 2023-02, Tongji University, Tongji University Hospital, Assistant Researcher
3. 2020-07 to 2021-08, École Normale Supérieure de Lyon (ENS Lyon)
Education
1. 2016-09 to 2020-07, École Normale Supérieure de Lyon (ENS Lyon), Immunology, PhD
2. 2016-09 to 2020-07, East China Normal University (ECNU), Biochemistry and Molecular Biology, PhD
3. 2013-09 to 2016-06, East China Normal University (ECNU), Biochemistry and Molecular Biology, Master’s Degree
获得国家自然科学基金青年项目、上海市浦江人才计划等项目。主要研究方向为细胞死亡的调控机制及其在疾病发生发展过程中的作用。包括：1）解析肿瘤微环境中细胞铁死亡调控肿瘤发生发展的机制和功能；2）探究应激压力对细胞命运的调控机制；3）揭示翻译后修饰对细胞死亡及相关疾病的调控机制及功能。
Tingting Niu has been awarded projects such as the National Natural Science Foundation of China Young Scientist Fund Project and the Shanghai Pujiang Talent Program. Main research directions focus on the regulatory mechanisms of cell death and their roles in the occurrence and development of diseases. This includes: 1) elucidating the mechanisms and functions by which ferroptosis in the tumor microenvironment regulates tumorigenesis and development; 2) investigating the regulatory mechanisms of stress on cell fate; 3) uncovering the regulatory mechanisms and functions of post-translational modifications in cell death and related diseases.
1.科研项目：
国家自然科学基金委员会, 青年科学基金项目（C类）[原青年科学基金项目], 30万, 主持
上海市科学技术委员会，22PJ1412000, 上海市浦江人才计划项目-A类(科研开发类), 30万元, 主持
同 济 大 学“中央高校基本科研业务费专项资金”，12万，主持
国家自然科学基金委员会, 专项项目, 200万元, 参与
国家自然科学基金委员会, 面上项目, 52万元, 参与
国家自然科学基金委员会, 面上项目, 54万元, 参与
2.发表文章：
(1) Niu, Tingting; De Rosny, Charlotte; Chautard, Severine; Rey, Amaury; Patoli, Danish;Groslambert, Marine; Cosson, Camille; Lagrange, Brice; Zhang, Zhirong; Visvikis, Orane; Hacot,Sabine; Hologne, Maggy; Walker, Olivier; Wong, Jeimin; Wang, Ping; Ricci, Romeo; Henry, Thomas;Boyer, Laurent; Petrilli, Virginie; Py, Benedicte F. ; NLRP3 phosphorylation in its LRR domain critically regulates inflammasome assembly, NATURE COMMUNICATIONS, 2021, 12(1)
(2) Cosson, Camille; Riou, Romane; Patoli, Danish; Niu, Tingting; Rey, Amaury; Groslambert,Marine; De Rosny, Charlotte; Chatre, Elodie; Allatif, Omran; Henry, Thomas; Venet, Fabienne;Milhavet, Florian; Boursier, Guilaine; Belot, Alexandre; Jamilloux, Yvan; Merlin, Etienne;Duquesne, Agnes; Grateau, Gilles; Savey, Lea; Maria, Alexandre Thibault Jacques; Pagnier, Anne;Poutrel, Solene; Lambotte, Olivier; Mallebranche, Coralie; Ardois, Samuel; Richer, Olivier;Lemelle, Irene; Rieux-Laucat, Frederic; Bader-Meunier, Brigitte; Amoura, Zahir; Melki, Isabelle;Cuisset, Laurence; Touitou, Isabelle; Geyer, Matthias; Georgin-Lavialle, Sophie; Py, Benedicte F.; Functional diversity of NLRP3 gain-of-function mutants associated with CAPS autoinflammation, JOURNAL OF EXPERIMENTAL MEDICINE, 2024, 221(5)
(3) Zhao, Xiaojie; Yu, Xin; Li, Wenge; Chen, Zhiyuan; Niu, Tingting; Weng, Xiaodong; Wang,Lei; Liu, Xiuheng ; CDK6 as a Biomarker for Immunotherapy, Drug Sensitivity, and Prognosis inBladder Cancer: Bioinformatics and Immunohistochemical Analysis, INTERNATIONAL JOURNAL OF MEDICAL SCIENCES, 2024, 21(12): 2414-2429
(4) J Pan; Q Deng; C Jiang; X Wang; T Niu; H Li; T Chen; J Jin; W Pan; X Cai; X Yang; M Lu; Xiao; P Wang ; USP37 directly deubiquitinates and stabilizes c-Myc in lung cancer, Oncogene,2015, 34(30): 3957-3967
(5) Jinxia Sun; Yi Luan; Dong Xiang; Xiao Tan; Hui Chen; Qi Deng; Jiaojiao Zhang; Minghui，Chen; Hongjun Huang; Weichao Wang; Tingting Niu; Wenjie Li; Hu Peng; Shuangxi Li; Lei Li; Wenwen Tang; Xiaotao Li; Dianqing Wu; Ping Wang ; The 11S Proteasome Subunit PSME3 Is a Positive Feedforward Regulator of NF-κB and Important for Host Defense against Bacterial Pathogens, Cell Reports, 2016, 14(4): 737-749
